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People take NMN supplements, as well as the best NAD+ supplements, to potentially help promote longevity, improve energy production, and protect their cells from oxidative stress

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Although such strategies have exhibited favorable outcomes in rheumatoid arthritis, their efficacy in OA remains debated, necessitating additional clinical trials (166, 167, 175)

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This prompted us to focus on screening natural compounds that can target the ferroptosis pathway, with particular emphasis on those capable of alleviating redox imbalancethe core driver of this cell death process